Following the successful completion of the lab trails, BudMore’s team is working on scaling up of the Nano-plasma reactor which uses the reactive ions from plasma discharge to deactivate pathogens in complex aquaculture systems.
Plasma is the fourth and the most abundant state of matter which contains a cocktail of free electrons, atoms, and molecules in the neutral or ionized state, UV, heat radiation, electromagnetic radiation, and reactive species.
The antimicrobial activity of plasma is directly linked to the amount of reactive species produced as well as plasma generated physical effects. At a suitable concentration, these plasma-generated species can attack each component of the cell to an extent that the cell no longer retains membrane integrity and loses complete functioning, leading to the cell death.
Pathogens (types) | Mechanism / Reason for inactivation |
Virus | The reactive ions present in plasma are responsible for virus inactivation through attacks on capsid protein and nucleic acids. |
Bacteria | Reactive species induces stress, damage cell wall or membrane and results in the to the release of cytoplasmic components. |
Fungus | The collective effect of reactive species causes morphological changes in the cell, ranging from reduction in size up to complete cellular damage. |
Parasite | Oxidative stress caused by the reactive oxygen species causes destruction. |
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